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Coeliac disease

The debate on coeliac disease screening—are we there yet?

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From Nature Reviews Gastroenterology & Hepatology

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The majority of patients with coeliac disease are undiagnosed, leading to debate about the utility of screening. The heterogeneous clinical presentation, which includes asymptomatic forms, can partially explain the difficulties faced when identifying coeliac disease. Now, Kurppa and colleagues add another element to the debate by strengthening the arguments for general screening.

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Figure 1: A proposal for an updated screening algorithm for coeliac disease in the general population.

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Authors and Affiliations

  1. Department of Pediatrics, Università Politecnica delle Marche, via F. Corridoni 11, Ancona, 60123, Italy

    Carlo Catassi

  2. Division of Pediatric Gastroenterology and Nutrition and Center for Celiac Research, Massachusetts General Hospital for Children, and Celiac Program, Harvard Medical School, 175 Cambridge Street CPZS-574, Boston, 02114, MA, USA

    Alessio Fasano

Authors
  1. Carlo Catassi
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  2. Alessio Fasano
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Correspondence to Carlo Catassi.

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Competing interests

C.C. is a consultant for Dr Schaer and Menarini Diagnostics. A.F. is a co-founder and stock holder in Alba Therapeutics.

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Catassi, C., Fasano, A. The debate on coeliac disease screening—are we there yet?. Nat Rev Gastroenterol Hepatol 11, 457–458 (2014). https://doi.org/10.1038/nrgastro.2014.119

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