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Rectal cancer

Landmark study comparing surgical approaches for rectal cancer

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Although numerous studies have reported the safety and efficacy of laparoscopic surgery for rectal cancer, the results of large multicentre randomized controlled trials have been lacking. A study including 1,103 patients has now shown that laparoscopic surgery for rectal cancer can result in similar safety, resection margins and completeness of resection with improved recovery compared with laparotomy.

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References

  1. van der Pas, M. H. et al. Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol. 14, 210–218 (2013).

    Article  PubMed  Google Scholar 

  2. Lacy, A. M. et al. Short-term outcome analysis of a randomized study comparing laparoscopic vs open colectomy for colon cancer. Surg. Endosc. 9, 1101–1105 (1995).

    CAS  PubMed  Google Scholar 

  3. Colon Cancer Laparoscopic or Open Resection Study Group et al. Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol. 10, 44–52 (2009).

  4. Jayne, D. G. et al. Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin. Oncol. 25, 3061–3068 (2007).

    Article  PubMed  Google Scholar 

  5. Weeks, J. C. et al. Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial. JAMA 287, 321–328 (2002).

    Article  PubMed  Google Scholar 

  6. Clinical Outcomes of Surgical Therapy Study Group. A comparison of laparoscopically assisted and open colectomy for colon cancer. N. Engl. J. Med. 350, 2050–2059 (2004).

  7. Steele, S. R., Brown, T. A., Rush, R. M. & Martin, M. J. Laparoscopic vs open colectomy for colon cancer: results from a large nationwide population-based analysis. J. Gastrointest. Surg. 12, 583–591 (2008).

    Article  PubMed  Google Scholar 

  8. Quirke, P. in Rectal Cancer Surgery: Optimisation, Standardisation, Documentation (eds Soreide, O. & Norstein, J.) 63–81 (Springer-Verlag, 1997).

    Book  Google Scholar 

  9. Levack, M. et al. Laparoscopy decreases anastomotic leak rate in sigmoid colectomy for diverticulitis. Arch. Surg. 146, 207–210 (2011).

    Article  PubMed  Google Scholar 

  10. Causey, M. W. et al. Laparoscopy impacts outcomes favorably following colectomy for ulcerative colitis: a critical analysis of the ACS-NSQIP database. Surg. Endosc. 27, 603–609 (2013).

    Article  PubMed  Google Scholar 

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Wexner, S. Landmark study comparing surgical approaches for rectal cancer. Nat Rev Gastroenterol Hepatol 10, 263–264 (2013). https://doi.org/10.1038/nrgastro.2013.61

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  • DOI: https://doi.org/10.1038/nrgastro.2013.61

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