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Risk of falls in cirrhosis predicted by psychometric testing

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Falls in cirrhosis may result from decreased muscle strength, unsuspected subcortical pathologies or psychoactive medications. Results of a prospective study reveal that cognitive dysfunction assessed by psychometric testing predicts the risk of falls in patients with cirrhosis. Early screening and effective preventive measures are required to limit the costs of falls in this population of patients.

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References

  1. Diamond, T. et al. Osteoporosis and skeletal fractures in chronic liver disease. Gut 1, 82–87 (1990).

    Article  Google Scholar 

  2. Román, E. et al. Minimal hepatic encephalopathy is associated with falls. Am. J. Gastroenterol. 106, 476–482 (2011).

    Article  Google Scholar 

  3. Soriano, G. et al. Cognitive dysfunction in cirrhosis is associated with falls. A prospective study. Hepatology http://dx.doi.org/10.1002/hep.25554.

  4. Weissenborn, K., Ennen, J. C., Schomerus, H., Ruckert, N. & Hecker, H. Neuropsychological characterization of hepatic encephalopathy. J. Hepatol. 34, 768–773 (2001).

    Article  CAS  Google Scholar 

  5. Lockwood, A. H., Weissenborn, K., Bokemeyer, M., Tietge, U. & Burchert, W. Correlations between cerebral glucose metabolism and neuropsychological test performance in nonalcoholic cirrhotics. Metab. Brain Dis. 17, 29–40 (2002).

    Article  Google Scholar 

  6. Burkhard, P. R., Delavelle, J., Du, P. R. & Spahr, L. Chronic parkinsonism associated with cirrhosis: a distinct subset of acquired hepatocerebral degeneration. Arch. Neurol. 60, 521–528 (2003).

    Article  Google Scholar 

  7. Spahr, L. et al. Increased blood manganese in cirrhotic patients: relationship to pallidal magnetic resonance signal hyperintensity and neurological symptoms. Hepatology 24, 1116–1120 (1996).

    Article  CAS  Google Scholar 

  8. Kril, J. J. & Butterworth, R. F. Diencephalic and cerebellar pathology in alcoholic and nonalcoholic patients with end-stage liver disease. Hepatology 26, 837–841 (1997).

    Article  CAS  Google Scholar 

  9. Pepersack, T. et al. Clinical relevance of thiamine status amongst hospitalized elderly patients. Gerontology 45, 96–101 (1999).

    Article  CAS  Google Scholar 

  10. van de Warrenburg, B. P., Steijns, J. A., Munneke, M., Kremer, B. P. & Bloem, B. R. Falls in degenerative cerebellar ataxias. Mov. Disord. 20, 497–500 (2005).

    Article  Google Scholar 

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Authors and Affiliations

  1. Neuroscience Research Unit, Hôpital Saint-Luc (University of Montreal), 1058 St-Denis Street, Montreal, H2X 3J4, QC, Canada

    Roger F. Butterworth

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  1. Roger F. Butterworth
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Butterworth, R. Risk of falls in cirrhosis predicted by psychometric testing. Nat Rev Gastroenterol Hepatol 9, 197–198 (2012). https://doi.org/10.1038/nrgastro.2012.22

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