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Prediction and prevention of peptic ulcer rebleeding

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Algorithms can predict the risk of rebleeding and mortality in patients with upper gastrointestinal bleeding, but not the risk of rebleeding following endoscopic treatment in patients with ulcers. A recent meta-analysis has addressed this issue, and could facilitate the development of methods to predict rebleeding and endoscopic treatments to reduce rebleeding.

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References

  1. Savides, T. S. & Jensen, D. M. in Sleisenger and Fordtran's Gastrointestinal and Liver Disease Pathophysiology/Diagnosis/Management 8th edn (eds Feldman, M., Friedman, L. S. & Brandt, L. J.) 285–322 (Saunders Elsevier, Philadelphia, 2010).

    Book  Google Scholar 

  2. Sung, J. J. et al. Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding: a randomized trial. Ann. Intern. Med. 150, 455–464 (2009).

    Article  Google Scholar 

  3. García-Iglesias, P. et al. Meta-analysis: predictors of rebleeding after endoscopic treatment of bleeding peptic ulcer. Aliment. Pharmacol. Ther. 34, 888–900 (2011).

    Article  Google Scholar 

  4. Rockall, T. A., Logan, R. F., Devlin, H. B. & Northfield, T. C. Risk assessment after acute upper gastrointestinal haemorrhage. Gut 38, 316–321 (1996).

    Article  CAS  Google Scholar 

  5. Rockall, T. A., Logan, R. F., Devlin, H. B. & Northfield, T. C. Selection of patients for early discharge or outpatient care after acute upper gastrointestinal haemorrhage. National Audit of Acute Upper Gastrointestinal Hemorrhage. Lancet 347, 1138–1140 (1996).

    Article  CAS  Google Scholar 

  6. Blatchford, O., Murray, W. R. & Blatchford, M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet 356, 1318–1321 (2000).

    Article  CAS  Google Scholar 

  7. Barkun, A. N. et al. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann. Intern. Med. 152, 101–113 (2010).

    Article  Google Scholar 

  8. Jensen, D. M. et al. Doppler ultrasound probe (DUP) as a guide to endoscopic hemostasis of ulcers with stigmata of recent hemorrhage (SRH) [abstract 347m]. Gastrointest. Endosc. 71, AB113 (2010).

    Article  Google Scholar 

  9. Wong, R. C. Nonvariceal upper gastrointestinal hemorrhage: probing beneath the surface. Gastroenterology 137, 1897–1902 (2009).

    Article  Google Scholar 

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Authors and Affiliations

  1. CURE DDRC, Room 318, Building 115, VA Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, 90073-1003, CA, USA

    Dennis M. Jensen

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  1. Dennis M. Jensen
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Competing interests

D. M. Jensen has received grants from AstraZeneca, Boston Scientific, Olympus, Pentax and US Endoscopy. He has been a consultant for AstraZeneca, Boston Scientific and US Endoscopy, and a speaker for Boston Scientific.

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Jensen, D. Prediction and prevention of peptic ulcer rebleeding. Nat Rev Gastroenterol Hepatol 9, 7–8 (2012). https://doi.org/10.1038/nrgastro.2011.243

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