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An ecosystem of cancer cell line factories to support a cancer dependency map

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Abstract

Jesse Boehm and Todd Golub call for an international effort to establish >10,000 cancer cell line models as a community resource. Cancer cell line factories will facilitate the creation of a cancer dependency map, connecting cancer genomics to therapeutic dependencies.

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Author information

Authors and Affiliations

  1. Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, 02142, Massachusetts, USA

    Jesse S. Boehm & Todd R. Golub

  2. Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, Massachusetts, USA

    Todd R. Golub

  3. Harvard Medical School, 25 Shattuck Street, Boston, 02115, Massachusetts, USA

    Todd R. Golub

  4. Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, 20815, Maryland, USA

    Todd R. Golub

Authors
  1. Jesse S. Boehm
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  2. Todd R. Golub
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Corresponding author

Correspondence to Jesse S. Boehm.

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Competing interests

The authors declare no competing financial interests.

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FURTHER INFORMATION

Cell Line Factory portal

Global Alliance for Genomics and Health

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Boehm, J., Golub, T. An ecosystem of cancer cell line factories to support a cancer dependency map. Nat Rev Genet 16, 373–374 (2015). https://doi.org/10.1038/nrg3967

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  • DOI: https://doi.org/10.1038/nrg3967

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