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H. Krumholz and J. Ross are funded by research agreements through Yale University from Medtronic and Johnson & Johnson (Janssen) to develop methods of clinical trial data sharing, by the US Centers for Medicare & Medicaid Services to develop and maintain performance measures, and by the US Food and Drug Administration to develop methods for post-market surveillance of medical devices. H. Krumholz chairs a cardiac scientific advisory board for UnitedHealth. The other authors do not have competing interests to report.
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Novel therapeutics approved by the FDA between 2005 and 2012 and their degree of innovation, stratified by drug type and therapeutic area. (PDF 113 kb)
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Downing, N., Krumholz, H., Ross, J. et al. Characterizing the US FDA's approach to promoting transformative innovation. Nat Rev Drug Discov 14, 740–741 (2015). https://doi.org/10.1038/nrd4734
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DOI: https://doi.org/10.1038/nrd4734
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