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Proteases

Unravelling the therapeutic activity of activated protein C

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ORIGINAL RESEARCH PAPERS

  1. Zhong, Z. et al. Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. J. Clin. Invest. 119, 3437–3449 (2009)

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  2. Xu, J. et al. Extracellular histones are major mediators of death in sepsis. Nature Med. 15, 1318–1321 (2009)

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Flight, M. Unravelling the therapeutic activity of activated protein C. Nat Rev Drug Discov 9, 20–21 (2010). https://doi.org/10.1038/nrd3082

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  • DOI: https://doi.org/10.1038/nrd3082

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