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Gynaecological cancer

Novel molecular subtypes of cervical cancer — potential clinical consequences

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The Cancer Genome Atlas Research Network recently published the most comprehensive, multi-omic molecular characterization of cervical cancers performed to date. The data reveal novel disease subtypes, and provide new insights into the aetiology and pathogenesis of cervical cancer. Importantly, the information obtained has potentially major clinical implications.

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Acknowledgements

C.J.L.M.M. is supported by the European Research Council (ERC advanced programme) via grant ERC-2012-AdG-322986-MASS-CARE.

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Correspondence to Chris J. L. M. Meijer.

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Competing interests

C.J.L.M.M. and R.D.M.S. have minority stakes in Self-Screen, a spin-off company of VU University Medical Center. C.J.L.M.M. has received speakers bureau from GSK, Menarini, Merck, Qiagen, Roche, and Seegene; has occasionally served on the scientific advisory board of GSK, Merck, Qiagen, and Roche; and has occasionally been a consultant for Genticel and Qiagen. Until April 2016, he had shares in Diassay.

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Meijer, C., Steenbergen, R. Novel molecular subtypes of cervical cancer — potential clinical consequences. Nat Rev Clin Oncol 14, 397–398 (2017). https://doi.org/10.1038/nrclinonc.2017.52

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