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Targeted therapies

Manufacturer sponsorship bias in economic analyses matters

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From Nature Reviews Clinical Oncology

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A qualitative study indicates that there is a positive selection bias towards favourable economic analysis of targeted therapies, when these are funded by the manufacturer. At a time of increasing budgetary constraints and public scrutiny of the relationship between industry and the professions, we need a more mixed economy of funding for this field.

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References

  1. Campbell, E. G. et al. A national survey of physician–industry relationships. N. Engl. J. Med. 356, 1742–1750 (2007).

    Article  CAS  Google Scholar 

  2. Djulbegovic, B., Angelotta, C., Knox, K. E. & Bennett, C. L. The sound and the fury: financial conflicts of interest in oncology. J. Clin. Oncol. 25, 3567–3569 (2007).

    Article  Google Scholar 

  3. Valachis, A., Polyzos, N. P., Nearchou, A., Lind, P. & Mauri, D. Financial relationships in economic analyses of targeted therapies in oncology. J. Clin. Oncol. http://dx.doi.org/10.1200/JCO.2011.38.6078.

  4. Jang, S., Chae, Y. K., Haddad, T. & Majhail, N. Conflict of interest in economic analyses of aromatase inhibitors in breast cancer: a systematic review. Breast Cancer Res. Treat. 121, 273–279 (2010).

    Article  Google Scholar 

  5. Barbieri, M. & Drummond, M. F. Conflict of interest in industry-sponsored economic evaluations: real or imagined? Curr. Oncol. Rep. 3, 410–413 (2010).

    Article  Google Scholar 

  6. Porter, M. E. in Evidence-based medicine and the changing nature of health care: 2007 Institute of Medicine (IOM) annual meeting summary 1st edn Ch. 14 (eds McClellan, M. B., McGinnis, J. M., Nabel, E. G. & Olsen, L. M.) 161–173 (National Academies Press, Washington DC, 2007).

    Google Scholar 

  7. Sullivan, R. et al. Delivering affordable cancer care in high-income countries. Lancet Oncol. 12, 933–980 (2011).

    Article  Google Scholar 

  8. US National Library of Medicine. ClinicalTrials.gov [online], (2012).

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Authors and Affiliations

  1. Nuffield Department of Clinical and Laboratory Sciences, University of Oxford, Oxford, OX3 7DQ, UK

    David Kerr

  2. Suez Canal University, Borg Alsafwa Centre, 3 Algeish Street, Port Said, 42111, Egypt

    Ahmed Elzawawy

Authors
  1. David Kerr
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  2. Ahmed Elzawawy
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Correspondence to David Kerr.

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The authors declare no competing financial interests.

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Kerr, D., Elzawawy, A. Manufacturer sponsorship bias in economic analyses matters. Nat Rev Clin Oncol 9, 309–310 (2012). https://doi.org/10.1038/nrclinonc.2012.75

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  • DOI: https://doi.org/10.1038/nrclinonc.2012.75

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