EGFR inhibitors provide benefit in patients with advanced and metastatic head and neck squamous cell carcinoma (HNSCC). Mass spectrometry profiling has been used to predict outcome in patients with HNSCC after EGFR inhibitor treatment, and may enable prior identification of patients most likely to benefit from these therapies. However, further validation in prospective studies is needed.
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Ang, MK., Hayes, D. Mass spectrometry in HNSCC—a peek at response prediction?. Nat Rev Clin Oncol 7, 193–195 (2010). https://doi.org/10.1038/nrclinonc.2010.35
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DOI: https://doi.org/10.1038/nrclinonc.2010.35
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