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Does nodal micrometastasis impact outcome in biliary cancer?

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Microscopic deposits of tumor cells in regional lymph nodes can be detected using immunohistochemical techniques in patients without conventional histopathological evidence of lymph-node involvement. In the case of bile duct cancer, these micrometastases have an intermediate prognostic significance between that of positive and negative conventional pathology.

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Authors and Affiliations

  1. Department of Transplantation and Hepatobiliary and Pancreatic Surgery, Churchill Hospital, Headington, OX3 7LJ, Oxford, UK

    Michael A. Silva & Peter J. Friend

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  1. Michael A. Silva
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  2. Peter J. Friend
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Correspondence to Peter J. Friend.

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The authors declare no competing financial interests.

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Silva, M., Friend, P. Does nodal micrometastasis impact outcome in biliary cancer?. Nat Rev Clin Oncol 7, 680–681 (2010). https://doi.org/10.1038/nrclinonc.2010.184

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