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Imaging

PET–CT imaging in non-small-cell lung cancer

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Imaging is performed in patients with early stage non-small-cell lung cancer (NSCLC) for disease staging and to identify the patients most likely to benefit from surgery. Two recent randomized trials compared conventional staging plus PET with conventional staging alone in patients with NSCLC. Patients who underwent PET were more likely to avoid futile thoracic surgery.

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References

  1. Pieterman, R. M. et al. Preoperative staging of non-small-cell lung cancer with positron-emission tomography. N. Engl. J. Med. 343, 254–261 (2000).

    Article  CAS  PubMed  Google Scholar 

  2. Ung, Y. C. et al. Lung cancer disease site group of Cancer Care Ontario's program in evidence-based care. 18F-fluorodeoxyglucose positron emission tomography in the diagnosis and staging of lung cancer: a systematic review. J. Natl Cancer Inst. 99, 1753–1767 (2007).

    Article  PubMed  Google Scholar 

  3. van Tinteren, H. et al. Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer: the PLUS multicentre randomised trial. Lancet 359, 1388–1393 (2002).

    Article  PubMed  Google Scholar 

  4. Viney, R. C. et al. Randomized controlled trial of the role of positron emission tomography in the management of stage I and II non-small-cell lung cancer. J. Clin. Oncol. 22, 2357–2362 (2004).

    Article  PubMed  Google Scholar 

  5. Herder, G. J. et al. POORT Study Group. Traditional versus up-front 18F-fluorodeoxyglucose positron emission tomography staging of non-small-cell lung cancer: a Dutch cooperative randomized study. J. Clin. Oncol. 24, 1800–1806 (2006).

    Article  PubMed  Google Scholar 

  6. Fischer, B. et al. Preoperative staging of lung cancer with combined CT–PET. N. Engl. J. Med. 361, 32–39 (2009).

    Article  CAS  PubMed  Google Scholar 

  7. Maziak, D. E. et al. Positron emission tomography in staging early lung cancer: a randomized trial. Ann. Intern. Med. 151, 221–228 (2009).

    Article  PubMed  Google Scholar 

  8. Iglehart, J. K. Health insurers and medical imaging policy—a work in progress. N. Engl. J. Med. 360, 1030–1037 (2009).

    Article  CAS  PubMed  Google Scholar 

  9. Ratner, R. et al. (Eds) Institute of Medicine: Initial National Priorities for Comparative Effectiveness Research. (National Academies, Washington DC, 2009).

    Google Scholar 

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Correspondence to Mark Levine.

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The authors declare no competing financial interests.

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Levine, M., Julian, J. PET–CT imaging in non-small-cell lung cancer. Nat Rev Clin Oncol 6, 619–620 (2009). https://doi.org/10.1038/nrclinonc.2009.163

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