Skip to main content

Advertisement

SpringerLink
Log in

Acute coronary syndromes

BNP measurement predicts AMI risk in the elderly

  • News & Views
  • Published:

From Nature Reviews Cardiology

View current issue Sign up to alerts

With the aging of the population, the frequency of acute myocardial infarction is rising most rapidly among the elderly, a subgroup at high risk of a fatal outcome. Lorgis et al. observe that N-terminal pro-brain natriuretic peptide, combined with a simple clinical risk score, provides an accurate estimate of prognosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Tahir, S. M., Price, L. L., Shah, P. B. & Welt, F. G. P. Eighteen year (1985–2002) analysis of incidence, mortality, and cardiac procedure outcomes of acute myocardial infarction in patients >65 years of age. Am. J. Cardiol. 101, 930–936 (2008).

    Article  Google Scholar 

  2. Lorgis, L. et al. Prognostic value of N-terminal pro-brain natriuretic peptide in elderly people with acute myocardial infarction: prospective observational study. BMJ 338, b1605 (2009).

    Article  CAS  Google Scholar 

  3. Braunwald, E. Biomarkers in heart failure. N. Engl. J. Med. 358, 2148–2159 (2008).

    Article  CAS  Google Scholar 

  4. Moe, G. W., Howlett, J., Januzzi, J. L. & Zowall, H. N-terminal pro-B-type natriuretic peptide testing improves the management of patients with suspected acute heart failure. Primary results of the Canadian prospective randomized multicenter IMPROVE-CHF study. Circulation 115, 3103–3110 (2007).

    Article  CAS  Google Scholar 

  5. Logeart, D. et al. Predischarge B-type natriuretic peptide assay for identifying patients at high risk of re-admission after decompensated heart failure. J. Am. Coll. Cardiol. 43, 635–641 (2004).

    Article  CAS  Google Scholar 

  6. de Lemos, J. A. et al. The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes. N. Engl. J. Med. 345, 1014–1021 (2001).

    Article  CAS  Google Scholar 

  7. Richards, A. M. et al. B-type natriuretic peptides and ejection fraction for prognosis after myocardial infarction. Circulation 107, 2786–2792 (2003).

    Article  CAS  Google Scholar 

  8. Sayama, H., Nakamura, Y., Saito, N. & Kinoshita, M. Why is the concentration of plasma brain natriuretic peptide in elderly inpatients greater than normal? Coron. Artery Dis. 10, 537–540 (1999).

    Article  CAS  Google Scholar 

  9. Kistorp, C. et al. N-terminal pro-brain natriuretic peptide, C-reactive protein, and urinary albumin levels as predictors of mortality and cardiovascular events in older adults. JAMA 293, 1609–1616 (2005).

    Article  CAS  Google Scholar 

  10. Fox, K. A. et al. Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE). BMJ 333, 1091 (2006).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Eugene Braunwald

Authors
  1. Eugene Braunwald
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Eugene Braunwald.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Braunwald, E. BNP measurement predicts AMI risk in the elderly. Nat Rev Cardiol 6, 503–504 (2009). https://doi.org/10.1038/nrcardio.2009.118

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrcardio.2009.118

  • Springer Nature Limited

Search

Navigation