Direct hit on mutant RAS

Oncogenes

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Ostrem, J. M. et al. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature http://dx.doi.org/10.1038/nature12796 (2013)

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Sarah Seton-Rogers
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Seton-Rogers, S. Direct hit on mutant RAS. Nat Rev Cancer 14, 8–9 (2014). https://doi.org/10.1038/nrc3650

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