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Cell cycle

Akt Skps through

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References

ORIGINAL RESEARCH PAPER

  1. Lin, H.-K. et al. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB Nature Cell Biol. 8 Mar 2009 (doi: 10.1038/ncb1849)

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  2. Gao, D. et al. Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APC–Cdh1-mediated Skp2 destruction Nature Cell Biol. 8 Mar 2009 (doi 10.1038/ncb1847)

FURTHER READING

  1. Frecas, D. & Pagano, M. Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer. Nature Rev. Cancer 8, 438–449 (2008).

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Authors and Affiliations

  1. UCSD–Nature Signaling Gateway,

    Emily J. Chenette

Authors
  1. Emily J. Chenette
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Chenette, E. Akt Skps through. Nat Rev Cancer 9, 316–317 (2009). https://doi.org/10.1038/nrc2649

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