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Cancer Immunotherapy

From local to global

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Nanoparticles that capture antigens produced in situ by tumours induce the 'abscopal' effect, improving the treatment of distant cancer lesions.

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Figure 1: Concept of enhancing an immune-mediated abscopal effect with intratumoural nanoparticle injection.

References

  1. Wilhelm, S. et al. Nat. Rev. Mater. 1, 16014 (2016).

    Article  CAS  Google Scholar 

  2. Min, Y. et al. Nat. Nanotech. 12, 877–882 (2017).

    Article  CAS  Google Scholar 

  3. Hammerich, L., Bhardwaj, N., Kohrt, H. E. & Brody, J. D. Immunotherapy 8, 315–330 (2016).

    Article  CAS  Google Scholar 

  4. Demaria, S. et al. Int. J. Radiat. Oncol. Biol. Phys. 58, 862–870 (2004).

    Article  Google Scholar 

  5. Postow, M. A. et al. N. Engl. J. Med. 366, 925–931 (2012).

    Article  CAS  Google Scholar 

  6. Karbach, J. et al. Cancer Immunol. Res. 2, 404–409 (2014).

    Article  Google Scholar 

  7. Stamell, E. F., Wolchok, J. D., Gnjatic, S., Lee, N. Y. & Brownell, I. Int. J. Radiat. Oncol. Biol. Phys. 85, 293–295 (2013).

    Article  Google Scholar 

  8. Shamay, Y. et al. Sci. Transl. Med. 8, 345ra87 (2016).

    Article  Google Scholar 

  9. He, C. et al. Nat. Commun. 7, 12499 (2016).

    Article  CAS  Google Scholar 

  10. Hao, Y. et al. Phys. Med. Biol. 61, N697–N707 (2016).

    Article  CAS  Google Scholar 

  11. Duan, X. et al. J. Am. Chem. Soc. 138, 16686–16695 (2016).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology and at the Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York,, 10029, New York

    Willem J. M. Mulder

  2. Department of Medical Biochemistry, Academic Medical Center, Amsterdam, 1105 AZ, The Netherlands

    Willem J. M. Mulder

  3. the Department of Medicine (Hematology and Medical Oncology Division), the Department of Oncological Sciences, and at the Tisch Cancer Institute and Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, 10029, New York, USA

    Sacha Gnjatic

Authors
  1. Willem J. M. Mulder
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  2. Sacha Gnjatic
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Correspondence to Willem J. M. Mulder or Sacha Gnjatic.

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Mulder, W., Gnjatic, S. From local to global. Nature Nanotech 12, 840–841 (2017). https://doi.org/10.1038/nnano.2017.196

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