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An iron age for cancer therapy

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Two reports show FDA-approved nanoparticles can kill cancer cells through iron- and reactive oxygen species-dependent mechanisms, offering new strategies for cancer treatment.

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Figure 1: Engineered nanoparticles kill cancer cells by manipulating iron levels and causing an accumulation of reactive oxygen species.

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Correspondence to Scott J. Dixon.

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Tarangelo, A., Dixon, S. An iron age for cancer therapy. Nature Nanotech 11, 921–922 (2016). https://doi.org/10.1038/nnano.2016.199

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