The binding and unbinding of single proteins to a gold nanorod can be detected with the help of the surface plasmon resonance of the nanorod.
This is a preview of subscription content, log in via an institution to check access.
References
Zijlstra, P., Paulo, P. M. R. & Orrit, M. Nature Nanotech. 7, 379–382 (2012).
Atwater, H. A. & Polman, A. Nature Mater. 9, 205–213 (2010).
Soukolis, C. M. & Wegener, M. Nature Photon. 9, 523–530 (2011).
Homola, J. Chem. Rev. 108, 462–493 (2008).
Stewart, M. E. et al. Chem. Rev. 108, 494–521 (2008).
Ament, I. et al. Nano Lett. 12, 1092–1095 (2012).
Giljohann, D. A. & Mirkin, C. A. Nature 462, 461–462 (2009).
Henzler-Wildman, K. & Kern, D. Nature 450, 964–972 (2007).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Käll, M. One molecule at a time. Nature Nanotech 7, 347–349 (2012). https://doi.org/10.1038/nnano.2012.92
Published:
Issue Date:
DOI: https://doi.org/10.1038/nnano.2012.92
- Springer Nature Limited
This article is cited by
-
Sensitivity Analysis of Gold Nanorod Biosensors for Single Molecule Detection
Plasmonics (2019)
-
Nanoscale Label-free Bioprobes to Detect Intracellular Proteins in Single Living Cells
Scientific Reports (2014)
-
Direct optical sensing of single unlabelled proteins and super-resolution imaging of their binding sites
Nature Communications (2014)