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AFM tackles osteoarthritis

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Current diagnostic tools detect cartilage degeneration only at advanced stages, but the atomic force microscope can now detect structural changes earlier, paving the way for treatment of joint diseases.

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Figure 1: The intermediate and late stages of osteoarthritis show up as narrowing of the joint space: the arrows in the left X-ray image point to a joint space in the knee of a healthy individual, whereas the arrows in the right image point to the reduced joint space in the knee of someone with intermediate-stage osteoarthritis.

DR E. WELKERLING

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Authors and Affiliations

  1. Thomas Aigner, Nicole Schmitz and Jochen Haag are in the Institute of Pathology, D-04103 Leipzig, Germany. Thomas.aigner@medizin.uni-leipzig.de,

    Thomas Aigner, Nicole Schmitz & Jochen Haag

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  1. Thomas Aigner
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  2. Nicole Schmitz
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  3. Jochen Haag
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Aigner, T., Schmitz, N. & Haag, J. AFM tackles osteoarthritis. Nature Nanotech 4, 144–145 (2009). https://doi.org/10.1038/nnano.2009.29

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