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A temporal frequency–dependent functional architecture in human V1 revealed by high-resolution fMRI

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Abstract

Although cortical neurons with similar functional properties often cluster together in a columnar organization, only ocular dominance columns, the columnar structure representing segregated anatomical input (from one of the two eyes), have been found in human primary visual cortex (V1). It has yet to be shown whether other columnar organizations that arise only from differential responses to stimulus properties also exist in human V1. Using high-resolution functional magnetic resonance imaging, we have found such a functional architecture containing domains that respond preferentially to either low or high temporal frequency.

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Figure 1: Anatomical details, temporal frequency–domains map and its reproducibility from a representative subject.
Figure 2: Characteristics of temporal frequency–domains map for the representative subject.

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Acknowledgements

We are indebted to our subjects for their time and efforts participating in the experiment. P.S. and J.L.G. were supported in part by postdoctoral fellowships from the Japan Society for the Promotion of Science.

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Authors and Affiliations

  1. Laboratory for Cognitive Brain Mapping, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, 351-0198, Saitama, Japan

    Pei Sun, Kenichi Ueno, R Allen Waggoner, Justin L Gardner, Keiji Tanaka & Kang Cheng

  2. Center for Neural Science and Department of Psychology, New York University, 6 Washington Place, New York, 10003, New York, USA

    Justin L Gardner

Authors
  1. Pei Sun
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  2. Kenichi Ueno
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  3. R Allen Waggoner
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  4. Justin L Gardner
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  5. Keiji Tanaka
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  6. Kang Cheng
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Corresponding author

Correspondence to Pei Sun.

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Supplementary Figures 1–10 Table 1 and Methods (PDF 1975 kb)

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Sun, P., Ueno, K., Waggoner, R. et al. A temporal frequency–dependent functional architecture in human V1 revealed by high-resolution fMRI. Nat Neurosci 10, 1404–1406 (2007). https://doi.org/10.1038/nn1983

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  • DOI: https://doi.org/10.1038/nn1983

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