Microglia, the brain's intrinsic immune cells, rapidly sense brain injury and help clear cellular debris. Haynes et al. now show that P2Y12 receptors are critical for activating microglia and directing them to the site of injury.
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Kettenmann, H. Triggering the brain's pathology sensor. Nat Neurosci 9, 1463–1464 (2006). https://doi.org/10.1038/nn1206-1463
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DOI: https://doi.org/10.1038/nn1206-1463
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