A new study in this issue demonstrates that two GABAergic motor neurons in C. elegans are excitatory at target muscles because GABA activates a ligand-gated cation conductance, which is structurally similar to several other ligand-gated channels.
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Goaillard, JM., Marder, E. Exciting guts with GABA. Nat Neurosci 6, 1121–1122 (2003). https://doi.org/10.1038/nn1103-1121
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DOI: https://doi.org/10.1038/nn1103-1121
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