A new study finds causal evidence that the lateral prefrontal cortex, implicated in executive function, is critical for making decisions in which forgoing a small immediate reward can lead to a better future outcome. These results suggest that this area provides a neural signal that biases behavior in favor of delaying gratification.
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References
Figner, B. et al. Nat. Neurosci. 13, 538–539 (2010).
Gogtay, N. et al. Proc. Natl. Acad. Sci. USA 101, 8174–8179 (2004).
McClure, S.M., Laibson, D.I., Loewenstein, G. & Cohen, J.D. Science 306, 503–507 (2004).
Weber, B.J. & Huettel, S.A. Brain Res. 1234, 104–115 (2008).
Kable, J.W. & Glimcher, P.W. Nat. Neurosci. 10, 1625–1633 (2007).
Monterosso, J.R. et al. Hum. Brain Mapp. 28, 383–393 (2007).
Boettiger, C.A. et al. J. Neurosci. 27, 14383–14391 (2007).
Shamosh, N.A. et al. Psychol. Sci. 19, 904–911 (2008).
Ballard, K. & Knutson, B. Neuroimage 45, 143–150 (2009).
Bjork, J.M., Momenan, R. & Hommer, D.W. Biol. Psychiatry 65, 710–713 (2009).
Fellows, L.K. & Farah, M.J. Neuropsychologia 43, 1214–1221 (2005).
Hare, T.A., Camerer, C.F. & Rangel, A. Science 324, 646–648 (2009).
Kable, J.W. & Glimcher, P.W. Neuron 63, 733–745 (2009).
Miller, E.K. & Cohen, J.D. Annu. Rev. Neurosci. 24, 167–202 (2001).
Knoch, D., Pascual-Leone, A., Meyer, K., Treyer, V. & Fehr, E. Science 314, 829–832 (2006).
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Kable, J. Just a little (lateral prefrontal) patience. Nat Neurosci 13, 523–524 (2010). https://doi.org/10.1038/nn0510-523
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DOI: https://doi.org/10.1038/nn0510-523
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