Skip to main content
Log in

Trafficking in emotions

  • News & Views
  • Published:

From Nature Neuroscience

View current issue Submit your manuscript

Postsynaptic receptor trafficking is associated with long-term synaptic plasticity, but whether this mechanism actually mediates learning is unclear. A new study shows that fear learning drives AMPA receptors into synapses in the lateral amygdala.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: The role of synaptic AMPA receptor insertion in emotional memories.

References

  1. Rumpel, S., LeDoux, J., Zador, A. & Malinow, R. Science 308, 83–88 (2005).

    Article  CAS  Google Scholar 

  2. Matynia, A., Kushner, S.A. & Silva, A.J. Annu. Rev. Genet. 36, 687–720 (2002).

    CAS  Google Scholar 

  3. Hayashi, Y. et al. Science 287, 2262–2267 (2000).

    Article  CAS  Google Scholar 

  4. Passafaro, M., Piech, V. & Sheng, M. Nat. Neurosci. 4, 917–926 (2001).

    Article  CAS  Google Scholar 

  5. Shi, S.H. et al. Science 284, 1811–1816 (1999).

    Article  CAS  Google Scholar 

  6. Takahashi, T., Svoboda, K. & Malinow, R. Science 299, 1585–1588 (2003).

    Article  CAS  Google Scholar 

  7. Shi, S., Hayashi, Y., Esteban, J.A. & Malinow, R. Cell 105, 331–343 (2001).

    Article  CAS  Google Scholar 

  8. Guzowski, J.F., McNaughton, B.L., Barnes, C.A. & Worley, P.F. Curr. Opin. Neurobiol. 11, 579–584 (2001).

    Article  CAS  Google Scholar 

  9. Zhang, W. & Linden, D.J. Nat. Rev. Neurosci. 4, 885–900 (2003).

    Article  CAS  Google Scholar 

  10. McKernan, M.G. & Shinnick-Gallagher, P. Nature 390, 607–611 (1997).

    Article  CAS  Google Scholar 

  11. Rogan, M.T., Staubli, U.V. & LeDoux, J.E. Nature 390, 604–607 (1997).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ehninger, D., Matynia, A. & Silva, A. Trafficking in emotions. Nat Neurosci 8, 548–550 (2005). https://doi.org/10.1038/nn0505-548

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn0505-548

  • Springer Nature America, Inc.

Navigation