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Disrupting addiction through the loss of drug-associated internal states

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Damage to the insula enables some smokers to quit easily and without relapse, reports a recent paper. The lesion may disrupt a a representation of internal bodily urges that is normally cued by learned drug associations.

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Figure 1: Drawing and fMRI image of the insula.

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Authors and Affiliations

  1. Department of Neuroscience, Menninger Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine, One Baylor Plaza, Houston, 77030, Texas, USA

    John A Dani & P Read Montague

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  1. John A Dani
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  2. P Read Montague
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Dani, J., Montague, P. Disrupting addiction through the loss of drug-associated internal states. Nat Neurosci 10, 403–404 (2007). https://doi.org/10.1038/nn0407-403

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