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Presynaptic NMDA receptors also make the switch

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A study shows that NR3A–containing presynaptic NMDA receptors regulate glutamate release, and that a switch in subunit composition underlies the developmental loss of spike timing–dependent LTD at cortical synapses.

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Figure 1: The developmental switch of receptor subunits that coincide with loss of tLTD.

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  1. Andrés Buonanno is in the Program of Developmental Neurobiology, Section on Molecular Neurobiology, Eunice Shriver Kennedy National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.,

    Andrés Buonanno

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  1. Andrés Buonanno
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Correspondence to Andrés Buonanno.

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Buonanno, A. Presynaptic NMDA receptors also make the switch. Nat Neurosci 14, 274–276 (2011). https://doi.org/10.1038/nn0311-274

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