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CREATEd viruses go global

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A Cre-dependent capsid selection method, CREATE, was used to produce adeno-associated viral vectors that allow gene delivery to the entire central and peripheral nervous systems, with multicolor labeling of single cells.

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Figure 1: Schematic of CREATE, a Cre-dependent AAV capsid selection method.

References

  1. Vandenberghe, L.H. & Auricchio, A. Gene Ther. 19, 162–168 (2012).

    Article  CAS  Google Scholar 

  2. Chan, K.Y. et al. Nat. Neurosci. 20, 1172–1179 (2017).

    Article  CAS  Google Scholar 

  3. Suzuki, K. et al. Nature 540, 144–149 (2016).

    Article  CAS  Google Scholar 

  4. Liem, L., van Dongen, E., Huygen, F.J., Staats, P. & Kramer, J. Reg. Anesth. Pain Med. 41, 511–519 (2016).

    Article  Google Scholar 

  5. Betley, J.N. & Sternson, S.M. Hum. Gene Ther. 22, 669–677 (2011).

    Article  CAS  Google Scholar 

  6. Carter, B.J. Mol. Ther. 10, 981–989 (2004).

    Article  CAS  Google Scholar 

  7. Dalkara, D. et al. Sci. Transl. Med. 5, 189ra76 (2013).

    Article  Google Scholar 

  8. Tervo, D.G.R. et al. Neuron 92, 372–382 (2016).

    Article  CAS  Google Scholar 

  9. Cronin, T. et al. EMBO Mol. Med. 6, 1175–1190 (2014).

    Article  CAS  Google Scholar 

  10. Zinn, E. et al. Cell Rep. 12, 1056–1068 (2015).

    Article  CAS  Google Scholar 

  11. Landegger, L.D. et al. Nat. Biotechnol. 35, 280–284 (2017).

    Article  CAS  Google Scholar 

  12. Yang, B. et al. Mol. Ther. 22, 1299–1309 (2014).

    Article  CAS  Google Scholar 

  13. Foust, K.D. et al. Nat. Biotechnol. 27, 59–65 (2009).

    Article  CAS  Google Scholar 

  14. Deverman, B.E. et al. Nat. Biotechnol. 34, 204–209 (2016).

    Article  CAS  Google Scholar 

  15. Hillier, D. et al. Nat. Neurosci. 20, 960–968 (2017).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biomedicine, Danish Research Institute of Translational Neuroscience—DANDRITE, Nordic EMBL Partnership for Molecular Medicine, Aarhus University, Aarhus, Denmark

    Keisuke Yonehara

  2. Neural Circuit Laboratories, Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

    Botond Roska

  3. University of Basel, Basel, Switzerland

    Botond Roska

Authors
  1. Keisuke Yonehara
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  2. Botond Roska
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Correspondence to Botond Roska.

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The authors declare no competing financial interests.

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Yonehara, K., Roska, B. CREATEd viruses go global. Nat Neurosci 20, 1041–1042 (2017). https://doi.org/10.1038/nn.4600

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