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Decoding and deorphanizing an olfactory map

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As conversion of odor signals to a two-dimensional map of activated glomeruli in the olfactory bulb is the key to odor recognition, decoding and deorphanizing of odorant receptors in the olfactory map is of great interest. Two genome-wide techniques now offer the ability to pair any odorant with its receptors.

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Figure 1: Two new strategies for deorphanizing ORs in the activated glomeruli of the olfactory bulb (OB) in the awake animal.

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Authors and Affiliations

  1. Hirofumi Nishizumi is in the Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo, Japan.,

    Hirofumi Nishizumi

  2. Hitoshi Sakano is in the Department of Brain Function, School of Medical Sciences, University of Fukui, Fukui, Japan.,

    Hitoshi Sakano

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  1. Hirofumi Nishizumi
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  2. Hitoshi Sakano
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Correspondence to Hitoshi Sakano.

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The authors declare no competing financial interests.

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Nishizumi, H., Sakano, H. Decoding and deorphanizing an olfactory map. Nat Neurosci 18, 1432–1433 (2015). https://doi.org/10.1038/nn.4121

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