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Imagine a journey through time and space

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The hippocampus, a structure critical for memory and navigation, contains both place and episodic cell assemblies. Synchronous input from the medial septum is crucial for inducing spatial and temporal neural sequences. These sequences are, in turn, necessary for constructing episodic cells and, in the absence of sensory input, place cells.

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Figure 1: Illustration of episodic sequences before and during medial septal inactivation.

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Correspondence to Lisa M Giocomo.

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Giocomo, L. Imagine a journey through time and space. Nat Neurosci 18, 163–164 (2015). https://doi.org/10.1038/nn.3926

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