Cortical neurons reduce spiking responses to repetitive sensory stimulation, but the perceptual impact of this adaptation has been difficult to assess. Work now shows that it has profound consequences for tactile perception.
References
Ollerenshaw, D.R., Zheng, H.J., Millard, D.C., Wang, Q. & Stanley, G.B. Neuron 81, 1152–1164 (2014).
Wang, Q., Webber, R.M. & Stanley, G.B. Nat. Neurosci. 13, 1534–1541 (2010).
Musall, S. et al. Nat. Neurosci. 17, 1567–1573 (2014).
Khatri, V., Hartings, J.A. & Simons, D.J. J. Neurophysiol. 92, 3244–3254 (2004).
Romo, R., Hernandez, A., Zainos, A. & Salinas, E. Nature 392, 387–390 (1998).
Sachidhanandam, S., Sreenivasan, V., Kyriakatos, A., Kremer, Y. & Petersen, C.C. Nat. Neurosci. 16, 1671–1677 (2013).
O'Connor, D.H. et al. Nat. Neurosci. 16, 958–965 (2013).
Luna, R., Hernandez, A., Brody, C.D. & Romo, R. Nat. Neurosci. 8, 1210–1219 (2005).
Gerdjikov, T.V., Bergner, C.G., Stuttgen, M.C., Waiblinger, C. & Schwarz, C. Neuron 65, 530–540 (2010).
von Heimendahl, M., Itskov, P.M., Arabzadeh, E. & Diamond, M.E. PLoS Biol. 5, e305 (2007).
Huber, D. et al. Nature 451, 61–64 (2008).
Jadhav, S.P., Wolfe, J. & Feldman, D.E. Nat. Neurosci. 12, 792–800 (2009).
Wolfe, J. et al. PLoS Biol. 6, e215 (2008).
Ritt, J.T., Andermann, M.L. & Moore, C.I. Neuron 57, 599–613 (2008).
Arabzadeh, E., Zorzin, E. & Diamond, M.E. PLoS Biol. 3, e17 (2005).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Yang, H., O'Connor, D. Cortical adaptation and tactile perception. Nat Neurosci 17, 1434–1436 (2014). https://doi.org/10.1038/nn.3847
Published:
Issue Date:
DOI: https://doi.org/10.1038/nn.3847
- Springer Nature America, Inc.
This article is cited by
-
Cholinergic modulation of sensory processing in awake mouse cortex
Scientific Reports (2021)