A study now finds early memory impairment in a mouse model of amyloid β43 (Aβ43)-overproducing familial Alzheimer's disease and suggests that this overlooked amyloidogenic Aβ species contributes to pathology.
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Bart De Strooper is a consultant for Janssen Pharmaceutica, Envivo Pharmaceuticals and Remynd NV. He also receives research funding from Janssen Pharmaceutica.
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Benilova, I., De Strooper, B. An overlooked neurotoxic species in Alzheimer's disease. Nat Neurosci 14, 949–950 (2011). https://doi.org/10.1038/nn.2871
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DOI: https://doi.org/10.1038/nn.2871
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