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Parasite pathogenesis: The dynamics of chronic malaria

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Rodent malaria parasites establish chronic infections through the sequential expression of subsets of variant antigen-encoding genes, a process that surprisingly appears to be independent of adaptive immunity.

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Figure 1: Infection of laboratory mice with P. chabaudi malaria parasites results in chronic infection.

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Correspondence to Kirk W. Deitsch.

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Deitsch, K. Parasite pathogenesis: The dynamics of chronic malaria. Nat Microbiol 2, 17039 (2017). https://doi.org/10.1038/nmicrobiol.2017.39

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