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Parasite pathogenesis: Breaching the wall for brain access

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Parasite access to the central nervous system is a severe complication of infection. Toxoplasma gondii can achieve this by directly infecting, replicating in and lysing blood–brain barrier endothelial cells.

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Figure 1: Toxoplasma gondii entry into the CNS.

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Authors and Affiliations

  1. Aarti Krishnan and Dominique Soldati-Favre are in the Department of Microbiology and Molecular Medicine, University of Geneva, CMU, 1 Rue Michel-Servet, CH-1211 Geneva 4, Switzerland.,

    Aarti Krishnan & Dominique Soldati-Favre

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  1. Aarti Krishnan
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  2. Dominique Soldati-Favre
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Correspondence to Aarti Krishnan.

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Krishnan, A., Soldati-Favre, D. Parasite pathogenesis: Breaching the wall for brain access. Nat Microbiol 1, 16014 (2016). https://doi.org/10.1038/nmicrobiol.2016.14

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