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Pathogens on aspirin: promising research and therapeutic applications

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An aspirin-modulated gene expression control circuit provides a powerful method to regulate expression of bacterial genes inside an infected host. This should provide a safe and easy way to study host-pathogen interactions, and may have direct therapeutic applications.

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Figure 1: Possible applications of the salicylate-modulated gene expression control circuit in S. enterica infecting a host.

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Authors and Affiliations

  1. Ohad Gal-Mor and B. Brett Finlay are at the Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada. bfinlay@interchange.ubc.ca,

    Ohad Gal-Mor & B Brett Finlay

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  1. Ohad Gal-Mor
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  2. B Brett Finlay
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Gal-Mor, O., Finlay, B. Pathogens on aspirin: promising research and therapeutic applications. Nat Methods 4, 893–894 (2007). https://doi.org/10.1038/nmeth1107-893

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