Skip to main content
Log in

A targeted approach to miRNA target identification

  • News & Views
  • Published:

From Nature Methods

View current issue Submit your manuscript

A targeted mass spectrometry method, selected reaction monitoring, is applied to validate predicted microRNA targets in Caenorhabditis elegans.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Detection of let-7 targets by SRM mass spectrometry in C. elegans.

References

  1. Jovanovic, M. et al. Nat. Methods 7, 837–842 (2010).

    Article  CAS  Google Scholar 

  2. Bartel, D.P. Cell 136, 215–233 (2009).

    Article  CAS  Google Scholar 

  3. Baek, D. et al. Nature 455, 64–71 (2008).

    Article  CAS  Google Scholar 

  4. Selbach, M. et al. Nature 455, 58–63 (2008).

    Article  CAS  Google Scholar 

  5. Bussing, I., Slack, F.J. & Grosshans, H. Trends Mol. Med. 14, 400–409 (2008).

    Article  Google Scholar 

  6. Croce, C.M. Nat. Rev. Genet. 10, 704–714 (2009).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andrew Grimson.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Grimson, A. A targeted approach to miRNA target identification. Nat Methods 7, 795–797 (2010). https://doi.org/10.1038/nmeth1010-795

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth1010-795

  • Springer Nature America, Inc.

This article is cited by

Navigation