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Fishing at the cellular level

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A platform for automated screening of zebrafish larvae in high throughput should allow detection of phenotypic changes in single cells.

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Figure 1: A high-throughput platform for zebrafish screening.

References

  1. Pardo-Martin, C. et al. Nat. Methods 7, 634–636 (2010).

    Article  CAS  Google Scholar 

  2. Zon, L.I. & Peterson, R.T. Nat. Rev. Drug Discov. 4, 35–44 (2005).

    Article  CAS  Google Scholar 

  3. Kokel, D. et al. Nat. Chem. Biol. 6, 231–237 (2010).

    Article  CAS  Google Scholar 

  4. Rihel, J. et al. Science 327, 348–351 (2010).

    Article  CAS  Google Scholar 

  5. Tran, T.C. et al. Cancer Res 67, 11386–11392 (2007).

    Article  CAS  Google Scholar 

  6. Fricke, C., Lee, J.S., Geiger-Rudolph, S., Bonhoeffer, F. & Chien, C.B. Science 292, 507–510 (2001).

    Article  CAS  Google Scholar 

  7. Kozlowski, D.J. & Weinberg, E.S. Methods Mol. Biol. 135, 349–355 (2000).

    CAS  PubMed  Google Scholar 

  8. Esengil, H., Chang, V., Mich, J.K., & Chen, J.K Nat. Chem. Biol. 3, 154–155 (2007).

    Article  CAS  Google Scholar 

  9. Sinha, D.K. et al. Zebrafish 7, 199–204 (2010).

    Article  CAS  Google Scholar 

  10. Hatta, K., Tsujii, H. & Omura, T. Nat. Protoc. 1, 960–967 (2006).

    Article  CAS  Google Scholar 

  11. Aramaki, S. & Hatta, K. Dev. Dyn. 235, 2192–2199 (2006).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Owen J. Tamplin and Leonard I. Zon are in the Stem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massacusetts, USA.,

    Owen J Tamplin & Leonard I Zon

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  1. Owen J Tamplin
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  2. Leonard I Zon
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Correspondence to Leonard I Zon.

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Competing interests

L.I.Z. is a founder and stock holder of Fate, Inc. and a scientific advisor for Stemgent.

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Tamplin, O., Zon, L. Fishing at the cellular level. Nat Methods 7, 600–601 (2010). https://doi.org/10.1038/nmeth0810-600

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