Advances in the application of microfluidics technology to biological assays using the model organism Caenorhabditis elegans help to automate otherwise time-consuming experiments.
References
Guo, S.X. et al. Nat. Methods 5, 531–533 (2008).
Chung, K., Crane, M.M. & Lu, H. Nat. Methods 5, 637–643 (2008).
Whitesides, G.M. Nature 442, 368–373 (2006).
Chronis, N., Zimmer, M. & Bargmann, C.I. Nat. Methods 4, 727–731 (2007).
Hulme, S.E., Shevkoplyas, S.S., Apfeld, J., Fontana, W. & Whitesides, G.M. Lab Chip 7, 1515–1523 (2007).
Rohde, C.B., Zeng, F., Gonzalez-Rubio, R., Angel, M. & Yanik, M.F. Proc. Natl. Acad. Sci. USA 104, 13891–13895 (2007).
Yanik, M.F. et al. Nature 432, 822 (2004).
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Hulme, S., Shevkoplyas, S. & Samuel, A. Microfluidics: streamlining discovery in worm biology. Nat Methods 5, 589–590 (2008). https://doi.org/10.1038/nmeth0708-589
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DOI: https://doi.org/10.1038/nmeth0708-589
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