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A triple threat to single molecules

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Three single-molecule methods promise to increase the time resolution of experiments, to allow better access to sparsely populated molecular states and to permit combinatorial high-throughput analysis.

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Figure 1: Three improved single-molecule techniques.

References

  1. Campos, L.A. et al. Nat. Methods 8, 143–146 (2011).

    Article  CAS  Google Scholar 

  2. Gambin, Y. et al. Nat. Methods 8, 239–241 (2011).

    Article  CAS  Google Scholar 

  3. Kim, S. et al. Nat. Methods 8, 242–245 (2011).

    Article  CAS  Google Scholar 

  4. Yang, W.Y. & Gruebele, M. Nature 423, 193–197 (2003).

    Article  CAS  Google Scholar 

  5. Liu, F. & Gruebele, M. J. Chem. Phys. 131, 195101 (2009).

    Article  Google Scholar 

  6. Chung, H.S., Louis, J.M. & Eaton, W.A. Proc. Natl. Acad. Sci. USA 106, 11837–11844 (2009).

    Article  CAS  Google Scholar 

  7. Eigen, M. & Maeyer, L.D. in Technique of Organic Chemistry (ed., A. Weissberger) 895–1054 (Interscience, 1963).

    Google Scholar 

  8. Uversky, V.N., Li, J. & Fink, A.L. J. Biol. Chem. 276, 44284–44296 (2001).

    Article  CAS  Google Scholar 

  9. Vandelinder, V., Ferreon, A.C., Gambin, Y., Deniz, A.A. & Groisman, A. Anal. Chem. 81, 6929–6935 (2009).

    Article  CAS  Google Scholar 

  10. Hansen, C.L., Sommer, M.O. & Quake, S.R. Proc. Natl. Acad. Sci. USA 101, 14431–14436 (2004).

    Article  CAS  Google Scholar 

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Correspondence to Martin Gruebele.

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Gruebele, M. A triple threat to single molecules. Nat Methods 8, 213–215 (2011). https://doi.org/10.1038/nmeth0311-213

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