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How the sum of its parts gets greater than the whole

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A single biomolecule carries information that becomes lost in an ensemble average. Methodological developments in imaging are now making it easier to access this hidden information in a live-cell context.

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Figure 1: Advantages of single-molecule imaging over ensemble imaging.

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Authors and Affiliations

  1. Biophysics Institute, Johannes Kepler University Linz, Altenbergerstr. 69, Linz, A-4040, Austria

    Mario Brameshuber & Gerhard J Schütz

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  1. Mario Brameshuber
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  2. Gerhard J Schütz
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Correspondence to Gerhard J Schütz.

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Brameshuber, M., Schütz, G. How the sum of its parts gets greater than the whole. Nat Methods 5, 133–134 (2008). https://doi.org/10.1038/nmeth0208-133

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