Skip to main content
Log in

Zinc-finger nucleases transition to the CoDA

  • News & Views
  • Published:

From Nature Methods

View current issue Submit your manuscript

Potent and easily produced custom zinc-finger nucleases will be game-changers for the field, at a time when the field itself is changing.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Engineering improvements to ZFNs.

References

  1. Sander, J.D. et al. Nat. Methods 8, 67–69 (2011).

    Article  CAS  Google Scholar 

  2. Kim, S., Lee, M.J., Kim, H., Kang, M. & Kim, J.-S. Nat. Methods 8, 7–9 (2011).

    Article  CAS  Google Scholar 

  3. Doyon, Y. et al. Nat. Methods 8, 74–79 (2011).

    Article  CAS  Google Scholar 

  4. Maeder, M.L. et al. Mol. Cell 31, 294–301 (2008).

    Article  CAS  Google Scholar 

  5. Urnov, F.D., Rebar, E.J., Holmes, M.C., Zhang, H.S. & Gregory, P.D., Nat. Rev. Genet. 11, 636–646 (2010).

    Article  CAS  Google Scholar 

  6. Kim, H.J., Lee, H.J., Kim, H., Cho, S.W. & Kim, J.S., Genome Res. 19, 1279–1288 (2009).

    Article  CAS  Google Scholar 

  7. Miller, J.C. et al. Nat. Biotechnol. 25, 778–785 (2007).

    Article  CAS  Google Scholar 

  8. Szczepek, M. et al. Nat. Biotechnol. 25, 786–793 (2007).

    Article  CAS  Google Scholar 

  9. Christian, M. et al. Genetics 186, 757–761 (2010).

    Article  CAS  Google Scholar 

  10. Li, T. et al. Nucleic Acids Res. advance online publication 10 August 2010 (doi: 10.1093/nar/gkq704).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to David J Segal.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Segal, D. Zinc-finger nucleases transition to the CoDA. Nat Methods 8, 53–55 (2011). https://doi.org/10.1038/nmeth0111-53

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth0111-53

  • Springer Nature America, Inc.

This article is cited by

Navigation