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A stress test for mass spectrometry–based proteomics

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A multilaboratory study attempts to dispel some of the notions of the irreproducibility of mass spectrometry–based proteomics by pinpointing where the methodological problems are and where challenges remain.

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Figure 1: The mountainous road to reproducible protein identification via mass spectrometry–based proteomics.

Kim Caesar

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Aebersold, R. A stress test for mass spectrometry–based proteomics. Nat Methods 6, 411–412 (2009). https://doi.org/10.1038/nmeth.f.255

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