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Sorting apples from oranges in single-cell expression comparisons

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Two methods for comparing single-cell expression data sets help address the challenge of integrating data across conditions and experiments.

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Figure 1: Computational methods match up data from multiple experiments.

Katie Vicari/Springer Nature

References

  1. Kiselev, V.Yu., Yiu, A. & Hemberg, M. Nat. Methods 15, 359–362 (2018).

    Article  CAS  Google Scholar 

  2. Alpert, A., Moore, L.S., Dubovik, T. & Shen-Orr, S.S. Nat. Methods 15, 267–270 (2018).

    Article  CAS  Google Scholar 

  3. Trapnell, C. et al. Nat. Biotechnol. 32, 381–386 (2014).

    Article  CAS  Google Scholar 

  4. Regev, A. et al. bioRxiv Preprint at http://biorxiv.org/content/early/2017/05/08/121202 (2017).

  5. Butler, A., Hoffman, P., Smibert, P., Papalexi, E. & Satija, R. Nat. Biotechnol. https://doi.org/10.1038/nbt.4096 (2018).

    Article  CAS  Google Scholar 

  6. Haghverdi, L., Lun, A.T.L., Morgan, M.D. & Marioni, J.C. Nat. Biotechnol. https://doi.org/10.1038/nbt.4091 (2018).

    Article  CAS  Google Scholar 

  7. Ibarra-Soria, X. et al. Nat. Cell Biol. 20, 127–134 (2018).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Haematology, Cambridge Institute for Medical Research, and Wellcome–MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK

    Fiona K Hamey & Berthold Göttgens

Authors
  1. Fiona K Hamey
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  2. Berthold Göttgens
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Correspondence to Berthold Göttgens.

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The authors declare no competing financial interests.

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Hamey, F., Göttgens, B. Sorting apples from oranges in single-cell expression comparisons. Nat Methods 15, 321–322 (2018). https://doi.org/10.1038/nmeth.4675

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