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Synthetic biology

Synthetic epigenetic memory

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Combining an inducible methyltransferase with a methylation-sensitive zinc finger creates an epigenetic memory circuit.

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References

  1. Maier, J.A.H. et al. Design of synthetic epigenetic circuits featuring memory effects and reversible switiching based on DNA methylation. Nat. Commun. 8, 15336 (2017).

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Rusk, N. Synthetic epigenetic memory. Nat Methods 14, 764 (2017). https://doi.org/10.1038/nmeth.4382

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  • DOI: https://doi.org/10.1038/nmeth.4382

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