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Trail-blAIZin new directions for conditional proteomics

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A reagent that labels proteins in close proximity to high concentrations of zinc is used to identify proteins with a role in zinc homeostasis.

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Figure 1: Conditional protein labeling triggered by metal-activated electrophiles.

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Correspondence to Brent R Martin.

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Motiwala, H., Martin, B. Trail-blAIZin new directions for conditional proteomics. Nat Methods 13, 917–918 (2016). https://doi.org/10.1038/nmeth.4043

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