A reagent that labels proteins in close proximity to high concentrations of zinc is used to identify proteins with a role in zinc homeostasis.
References
Savitski, M.M. et al. Science 346, 1255784 (2014).
Cravatt, B.F., Wright, A.T. & Kozarich, J.W. Annu. Rev. Biochem. 77, 383–414 (2008).
Savas, J.N., Toyama, B.H., Xu, T., Yates, J.R. III & Hetzer, M.W. Science 335, 942 (2012).
Miki, T. et al. Nat. Methods 13, 931–937 (2016).
Andreini, C., Banci, L., Bertini, I. & Rosato, A. J. Proteome Res. 5, 196–201 (2006).
Carpenter, M.C., Lo, M.N. & Palmer, A.E. Arch. Biochem. Biophys. http://dx.doi.org/10.1016/j.abb.2016.08.018 (2016).
Pace, N.J. & Weerapana, E. ACS Chem. Biol. 9, 258–265 (2014).
Finney, L.A. & O'Halloran, T.V. Science 300, 931–936 (2003).
Rhee, H.W. et al. Science 339, 1328–1331 (2013).
Roux, K.J., Kim, D.I., Raida, M. & Burke, B. J. Cell Biol. 196, 801–810 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Motiwala, H., Martin, B. Trail-blAIZin new directions for conditional proteomics. Nat Methods 13, 917–918 (2016). https://doi.org/10.1038/nmeth.4043
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.4043
- Springer Nature America, Inc.