Two approaches for robust, objective segmentation of single-molecule localization data promise better quantitative insights into protein clustering from super-resolution imaging methods.
This is a preview of subscription content, log in via an institution to check access.
References
Rubin-Delanchy, P. et al. Nat. Methods 12, 1072–1076 (2015).
Levet, F. et al. Nat. Methods 12, 1065–1071 (2015).
Kiskowski, M.A., Hancock, J.F. & Kenworthy, A.K. Biophys. J. 97, 1095–1103 (2009).
Owen, D.M. et al. J. Biophotonics 3, 446–454 (2010).
Baddeley, D., Cannell, M.B. & Soeller, C. Microsc. Microanal. 16, 64–72 (2010).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Baddeley, D. Detecting nano-scale protein clustering. Nat Methods 12, 1019–1020 (2015). https://doi.org/10.1038/nmeth.3641
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.3641
- Springer Nature America, Inc.