Skip to main content
SpringerLink
Log in

Co-opting CRISPR to deliver functional RNAs

  • News & Views
  • Published:

From Nature Methods

View current issue Submit your manuscript

Portions of the CRISPR-Cas9 guide RNA can be reworked to carry functional RNA cargos to genomic loci.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: CRISP-Disp delivers RNA cargos in the cell.

References

  1. Shechner, D.M., Hacisuleyman, E., Younger, S.T. & Rinn, J.L. Nat. Methods 12, 664–670 (2015).

    Article  CAS  Google Scholar 

  2. Jinek, M. et al. Science 337, 816–821 (2012).

    Article  CAS  Google Scholar 

  3. Gilbert, L.A. et al. Cell 154, 442–451 (2013).

    Article  CAS  Google Scholar 

  4. Ryan, O.W. et al. eLife 3, e03703 (2014).

    Article  Google Scholar 

  5. Briner, A.E. et al. Mol. Cell 56, 333–339 (2014).

    Article  CAS  Google Scholar 

  6. Konermann, S. et al. Nature 517, 583–588 (2015).

    Article  CAS  Google Scholar 

  7. Zalatan, J.G. et al. Cell 160, 339–350 (2015).

    Article  CAS  Google Scholar 

  8. Nissim, L., Perli, S.D., Fridkin, A., Perez-Pinera, P. & Lu, T.K. Mol. Cell 54, 698–710 (2014).

    Article  CAS  Google Scholar 

  9. O'Connell, M.R. et al. Nature 516, 263–266 (2014).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pei-Chun Lin and Jacob E. Corn are with the Innovative Genomics Initiative, University of California, Berkeley, Berkeley, California, USA.,

    Pei-Chun Lin & Jacob E Corn

Authors
  1. Pei-Chun Lin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jacob E Corn
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jacob E Corn.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lin, PC., Corn, J. Co-opting CRISPR to deliver functional RNAs. Nat Methods 12, 613–614 (2015). https://doi.org/10.1038/nmeth.3452

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.3452

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation