Skip to main content
SpringerLink
Log in

Toward high-throughput biomechanical phenotyping of single molecules

  • News & Views
  • Published:

From Nature Methods

View current issue Submit your manuscript

Two high-throughput single-molecule force spectroscopy platforms expand the reach of this technology for biomechanical molecular phenotyping.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1

References

  1. Otten, M. et al. Nat. Methods 11, 1127–1130 (2014).

    Article  CAS  Google Scholar 

  2. Sitters, G. et al. Nat. Methods 12, 47–50 (2015).

    Article  CAS  Google Scholar 

  3. Neuman, K.C. & Nagy, A. Nat. Methods 5, 491–505 (2008).

    Article  CAS  Google Scholar 

  4. Müller, D.J. & Dufrene, Y.F. Nat. Nanotechnol. 3, 261–269 (2008).

    Article  Google Scholar 

  5. Maerkl, S.J. & Quake, S.R. Science 315, 233–237 (2007).

    Article  CAS  Google Scholar 

  6. Fordyce, P.M. et al. Nat. Biotechnol. 28, 970–975 (2010).

    Article  CAS  Google Scholar 

  7. Struckmeier, J. et al. Nanotechnology 19, 384020 (2008).

    Article  Google Scholar 

  8. Chiou, P.Y., Ohta, A.T. & Wu, M.C. Nature 436, 370–372 (2005).

    Article  CAS  Google Scholar 

  9. De Vlaminck, I. et al. Nano Lett. 11, 5489–5493 (2011).

    Article  Google Scholar 

  10. Otten, M., Wolf, P. & Gaub, H.E. Lab Chip 13, 4198–4204 (2013).

    Article  CAS  Google Scholar 

  11. Streets, A.M. & Huang, Y. Curr. Opin. Biotechnol. 25, 69–77 (2014).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Savaş Tay and Daniel J Müller are in the Department of Biosystems Science and Engineering, David Alsteens, ETH Zürich, Basel, Switzerland.,

    David Alsteens, Savaş Tay & Daniel J Müller

Authors
  1. David Alsteens
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Savaş Tay
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Daniel J Müller
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Daniel J Müller.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Alsteens, D., Tay, S. & Müller, D. Toward high-throughput biomechanical phenotyping of single molecules. Nat Methods 12, 45–46 (2015). https://doi.org/10.1038/nmeth.3216

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.3216

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation