Skip to main content
Log in

The I-TASSER Suite: protein structure and function prediction

  • Correspondence
  • Published:

From Nature Methods

View current issue Submit your manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Flow chart and illustrative examples of I-TASSER Suite for protein structure and function modeling.

Accession codes

Accessions

Protein Data Bank

References

  1. Moult, J., Fidelis, K., Kryshtafovych, A., Schwede, T. & Tramontano, A. Proteins 82 (suppl. 2), 1–6 (2014).

    Article  CAS  Google Scholar 

  2. Haas, J. et al. Database (Oxford) 2013, bat031 (2013).

    Article  Google Scholar 

  3. Roy, A., Kucukural, A. & Zhang, Y. Nat. Protoc. 5, 725–738 (2010).

    Article  CAS  Google Scholar 

  4. Yang, J., Roy, A. & Zhang, Y. Bioinformatics 29, 2588–2595 (2013).

    Article  CAS  Google Scholar 

  5. Yang, J., Roy, A. & Zhang, Y. Nucleic Acids Res. 41, D1096–D1103 (2013).

    Article  CAS  Google Scholar 

  6. Zhang, Y. Proteins 82 (suppl. 2), 175–187 (2014).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We are grateful to many of the I-TASSER Suite users whose feedback helped improve the functionality and usability of the programs. The work was supported in part by the US National Science Foundation Career Award (DBI 0746198) and the US National Institute of General Medical Sciences (GM083107, GM084222).

Author information

Authors and Affiliations

Authors

Contributions

Y.Z. conceived of the research; J.Y., R.Y., A.R., D.X. and J.P. performed research and created and tested the I-TASSER Suite package; J.Y., R.Y., A.R. and Y.Z. wrote the manuscript.

Corresponding author

Correspondence to Yang Zhang.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Text and Tables

Supplementary Tables 1–3 and Supplementary Methods (PDF 5909 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yang, J., Yan, R., Roy, A. et al. The I-TASSER Suite: protein structure and function prediction. Nat Methods 12, 7–8 (2015). https://doi.org/10.1038/nmeth.3213

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.3213

  • Springer Nature America, Inc.

This article is cited by

Navigation