Researchers use sequence coevolution information to predict the structures of protein complexes.
References
Hopf, T.A. et al. Sequence co-evolution gives 3D contacts and structures of protein complexes. eLife 3, e03430 (2014).
Ovchinnikov, S. et al. Robust and accurate prediction of residue-residue interactions across protein interfaces using evolutionary information. eLife 3, e02030 (2014).
Rights and permissions
About this article
Cite this article
Doerr, A. Using evolution to predict structure. Nat Methods 11, 1192–1193 (2014). https://doi.org/10.1038/nmeth.3198
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.3198
- Springer Nature America, Inc.